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Revisiting RNA-directed DNA methylation

RNA-directed DNA methylation (RdDM) involves sequence-specific guiding of the de novo methylation machinery to complementary genomic DNA by RNA molecules. It is still elusive whether guide RNAs bind directly to DNA or to nascent transcripts produced from it. Even the nature of the guide RNAs is not...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dalakouras, Athanasios, Wassenegger, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672289/
https://ncbi.nlm.nih.gov/pubmed/23324611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.23542
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