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Heme degradation by Staphylococcus aureus IsdG and IsdI liberates formaldehyde rather than carbon monoxide

IsdG and IsdI from Staphylococcus aureus are novel heme degrading enzymes containing unusually non-planar (ruffled) heme. While canonical heme degrading enzymes, heme oxygenases, catalyze heme degradation coupled with the release of CO, in this study we demonstrate that the primary C1 product of the...

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Bibliografski detalji
Glavni autori: Matsui, Toshitaka, Nambu, Shusuke, Ono, Yukari, Goulding, Celia W., Tsumoto, Kouhei, Ikeda-Saito, Masao
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672231/
https://ncbi.nlm.nih.gov/pubmed/23600533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400382p
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