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Heme degradation by Staphylococcus aureus IsdG and IsdI liberates formaldehyde rather than carbon monoxide

IsdG and IsdI from Staphylococcus aureus are novel heme degrading enzymes containing unusually non-planar (ruffled) heme. While canonical heme degrading enzymes, heme oxygenases, catalyze heme degradation coupled with the release of CO, in this study we demonstrate that the primary C1 product of the...

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Detalhes bibliográficos
Main Authors: Matsui, Toshitaka, Nambu, Shusuke, Ono, Yukari, Goulding, Celia W., Tsumoto, Kouhei, Ikeda-Saito, Masao
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672231/
https://ncbi.nlm.nih.gov/pubmed/23600533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400382p
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