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Heme degradation by Staphylococcus aureus IsdG and IsdI liberates formaldehyde rather than carbon monoxide

IsdG and IsdI from Staphylococcus aureus are novel heme degrading enzymes containing unusually non-planar (ruffled) heme. While canonical heme degrading enzymes, heme oxygenases, catalyze heme degradation coupled with the release of CO, in this study we demonstrate that the primary C1 product of the...

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Autori principali: Matsui, Toshitaka, Nambu, Shusuke, Ono, Yukari, Goulding, Celia W., Tsumoto, Kouhei, Ikeda-Saito, Masao
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672231/
https://ncbi.nlm.nih.gov/pubmed/23600533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400382p
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