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Heme degradation by Staphylococcus aureus IsdG and IsdI liberates formaldehyde rather than carbon monoxide

IsdG and IsdI from Staphylococcus aureus are novel heme degrading enzymes containing unusually non-planar (ruffled) heme. While canonical heme degrading enzymes, heme oxygenases, catalyze heme degradation coupled with the release of CO, in this study we demonstrate that the primary C1 product of the...

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Autors principals: Matsui, Toshitaka, Nambu, Shusuke, Ono, Yukari, Goulding, Celia W., Tsumoto, Kouhei, Ikeda-Saito, Masao
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672231/
https://ncbi.nlm.nih.gov/pubmed/23600533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400382p
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