MicroRNA 21 promotes fibrosis of the kidney by silencing metabolic pathways

Scarring of the kidney is a major public health concern, directly promoting loss of kidney function. In order to understand the role of microRNA (miRNA) in the progression of kidney scarring in response to injury, we investigated changes in miRNA expression in two kidney fibrosis models, and identif...

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Bibliografiske detaljer
Main Authors: Chau, B. Nelson, Xin, Cuiyan, Hartner, Jochen, Ren, Shuyu, Castano, Ana P., Linn, Geoffrey, Li, Jian, Tran, Phong T, Kaimal, Vivek, Huang, Xinqiang, Chang, Aaron N, Li, Shenyan, Kalra, Aarti, Grafals, Monica, Portilla, Didier, MacKenna, Deidre A., Orkin, Stuart H., Duffield, Jeremy S.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672221/
https://ncbi.nlm.nih.gov/pubmed/22344686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3003205
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