Regulation of the kinase RSK1 by arsenic trioxide and generation of antileukemic responses

Arsenic Trioxide (As(2)O(3)) is one of the most effective agents in the treatment of acute promyelocytic leukemia (APL), but has no significant efficacy in other forms of AML. The mechanisms of relative resistance of non-APL cells are not well understood, but emerging evidence suggests that activati...

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Autori principali: Galvin, John P., Altman, Jessica K., Szilard, Amy, Goussetis, Dennis J., Vakana, Eliza, Sassano, Antonella, Platanias, Leonidas C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672185/
https://ncbi.nlm.nih.gov/pubmed/23377826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.23760
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