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Regulation of the kinase RSK1 by arsenic trioxide and generation of antileukemic responses

Arsenic Trioxide (As(2)O(3)) is one of the most effective agents in the treatment of acute promyelocytic leukemia (APL), but has no significant efficacy in other forms of AML. The mechanisms of relative resistance of non-APL cells are not well understood, but emerging evidence suggests that activati...

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Detalhes bibliográficos
Main Authors: Galvin, John P., Altman, Jessica K., Szilard, Amy, Goussetis, Dennis J., Vakana, Eliza, Sassano, Antonella, Platanias, Leonidas C.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672185/
https://ncbi.nlm.nih.gov/pubmed/23377826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.23760
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