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Arsenic Trioxide-Dependent Activation of Thousand-and-One Amino Acid Kinase 2 and Transforming Growth Factor-β-Activated Kinase 1

Arsenic trioxide (As(2)O(3)) has potent antileukemic properties in vitro and in vivo, but the mechanisms by which it generates its effects on target leukemic cells are not well understood. Understanding cellular mechanisms and pathways that are activated in leukemic cells to control the generation o...

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Autors principals: McNeer, Jennifer L., Goussetis, Dennis J., Sassano, Antonella, Dolniak, Blazej, Kroczynska, Barbara, Glaser, Heather, Altman, Jessica K., Platanias, Leonidas C.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872974/
https://ncbi.nlm.nih.gov/pubmed/20159944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.061507
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