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BCR-ABL1-induced leukemogenesis and autophagic targeting by arsenic trioxide

We have recently shown that arsenic trioxide (As(2)O(3)) is a potent inducer of autophagic degradation of the BCR-ABL1 oncoprotein, which is the cause of chronic myeloid leukemia (CML) and Ph+ acute lymphoid leukemia (Ph+ ALL). Our recently published work has shown that pharmacological inhibition of...

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Bibliografiset tiedot
Päätekijät: Goussetis, Dennis J., Gounaris, Elias, Platanias, Leonidas C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Landes Bioscience 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542221/
https://ncbi.nlm.nih.gov/pubmed/23051894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22259
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