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BCR-ABL1-induced leukemogenesis and autophagic targeting by arsenic trioxide
We have recently shown that arsenic trioxide (As(2)O(3)) is a potent inducer of autophagic degradation of the BCR-ABL1 oncoprotein, which is the cause of chronic myeloid leukemia (CML) and Ph+ acute lymphoid leukemia (Ph+ ALL). Our recently published work has shown that pharmacological inhibition of...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Landes Bioscience
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3542221/ https://ncbi.nlm.nih.gov/pubmed/23051894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22259 |
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