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Integrative genomic analysis of CREB defines a critical role for transcription factor networks in mediating the fed/fasted switch in liver

BACKGROUND: Metabolic homeostasis in mammals critically depends on the regulation of fasting-induced genes by CREB in the liver. Previous genome-wide analysis has shown that only a small percentage of CREB target genes are induced in response to fasting-associated signaling pathways. The precise mol...

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Detalhes bibliográficos
Main Authors: Everett, Logan J, Lay, John Le, Lukovac, Sabina, Bernstein, Diana, Steger, David J, Lazar, Mitchell A, Kaestner, Klaus H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671974/
https://ncbi.nlm.nih.gov/pubmed/23682854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-337
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