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Targeting Sonic Hedgehog Signaling by Compounds and Derivatives from Natural Products

Cancer stem cells (CSCs) are a major cause of cancer treatment failure, relapse, and drug resistance and are known to be responsible for cancer cell invasion and metastasis. The Sonic hedgehog (Shh) signaling pathway is crucial to embryonic development. Intriguingly, the aberrant activation of the S...

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Autores principales: Huang, Yu-Chuen, Chao, K. S. Clifford, Liao, Hui-Fen, Chen, Yu-Jen
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671665/
https://ncbi.nlm.nih.gov/pubmed/23762158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/748587
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