Small-Molecule Synthetic Compound Norcantharidin Reverses Multi-Drug Resistance by Regulating Sonic Hedgehog Signaling in Human Breast Cancer Cells

Multi-drug resistance (MDR), an unfavorable factor compromising treatment efficacy of anticancer drugs, involves upregulated ATP binding cassette (ABC) transporters and activated Sonic hedgehog (Shh) signaling. By preparing human breast cancer MCF-7 cells resistant to doxorubicin (DOX), we examined...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chen, Yu-Jen, Kuo, Cheng-Deng, Chen, Szu-Han, Chen, Wei-Jen, Huang, Wen-Chien, Chao, K. S. Clifford, Liao, Hui-Fen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352857/
https://ncbi.nlm.nih.gov/pubmed/22615870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037006
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