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Targeting Sonic Hedgehog Signaling by Compounds and Derivatives from Natural Products

Cancer stem cells (CSCs) are a major cause of cancer treatment failure, relapse, and drug resistance and are known to be responsible for cancer cell invasion and metastasis. The Sonic hedgehog (Shh) signaling pathway is crucial to embryonic development. Intriguingly, the aberrant activation of the S...

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Detalhes bibliográficos
Main Authors: Huang, Yu-Chuen, Chao, K. S. Clifford, Liao, Hui-Fen, Chen, Yu-Jen
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671665/
https://ncbi.nlm.nih.gov/pubmed/23762158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/748587
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