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Targeting Sonic Hedgehog Signaling by Compounds and Derivatives from Natural Products

Cancer stem cells (CSCs) are a major cause of cancer treatment failure, relapse, and drug resistance and are known to be responsible for cancer cell invasion and metastasis. The Sonic hedgehog (Shh) signaling pathway is crucial to embryonic development. Intriguingly, the aberrant activation of the S...

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Autori principali: Huang, Yu-Chuen, Chao, K. S. Clifford, Liao, Hui-Fen, Chen, Yu-Jen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671665/
https://ncbi.nlm.nih.gov/pubmed/23762158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/748587
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