Ecdysone triggered PGRP-LC expression controls Drosophila innate immunity

Throughout the animal kingdom, steroid hormones have been implicated in the defense against microbial infection, but how these systemic signals control immunity is unclear. Here, we show that the steroid hormone ecdysone controls the expression of the pattern recognition receptor PGRP-LC in Drosophi...

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Bibliographic Details
Main Authors: Rus, Florentina, Flatt, Thomas, Tong, Mei, Aggarwal, Kamna, Okuda, Kendi, Kleino, Anni, Yates, Elisabeth, Tatar, Marc, Silverman, Neal
Format: Artigo
Language:Inglês
Published: European Molecular Biology Organization 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671248/
https://ncbi.nlm.nih.gov/pubmed/23652443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.100
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