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Drosophila peptidoglycan recognition protein LC (PGRP-LC) acts as a signal-transducing innate immune receptor

Drosophila peptidoglycan recognition protein LC (PGRP-LC), a transmembrane protein required for the response to bacterial infection, acts at the top of a cytoplasmic signaling cascade that requires the death-domain protein Imd and an IκB kinase to activate Relish, an NF-κB family member. It is not c...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Choe, Kwang-Min, Lee, Hyangkyu, Anderson, Kathryn V.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC545828/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15657141/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0404952102
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