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Ecdysone triggered PGRP-LC expression controls Drosophila innate immunity

Throughout the animal kingdom, steroid hormones have been implicated in the defense against microbial infection, but how these systemic signals control immunity is unclear. Here, we show that the steroid hormone ecdysone controls the expression of the pattern recognition receptor PGRP-LC in Drosophi...

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Detalhes bibliográficos
Main Authors: Rus, Florentina, Flatt, Thomas, Tong, Mei, Aggarwal, Kamna, Okuda, Kendi, Kleino, Anni, Yates, Elisabeth, Tatar, Marc, Silverman, Neal
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671248/
https://ncbi.nlm.nih.gov/pubmed/23652443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.100
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