Ecdysone triggered PGRP-LC expression controls Drosophila innate immunity

Throughout the animal kingdom, steroid hormones have been implicated in the defense against microbial infection, but how these systemic signals control immunity is unclear. Here, we show that the steroid hormone ecdysone controls the expression of the pattern recognition receptor PGRP-LC in Drosophi...

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Main Authors: Rus, Florentina, Flatt, Thomas, Tong, Mei, Aggarwal, Kamna, Okuda, Kendi, Kleino, Anni, Yates, Elisabeth, Tatar, Marc, Silverman, Neal
Format: Artigo
Sprog:Inglês
Udgivet: European Molecular Biology Organization 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671248/
https://ncbi.nlm.nih.gov/pubmed/23652443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.100
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