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Overproduction of protein p53 contributes to simian virus 40-mediated transformation.

The possible involvement of p53 overproduction in simian virus 40 (SV40)mediated transformation was studied by using the rat embryo fibroblast focus formation assay. Transformation by wild-type SV40 was enhanced two- to threefold by cotransfection of a plasmid overexpressing mouse p53. More signific...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Michalovitz, D, Eliyahu, D, Oren, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1986
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC367102/
https://ncbi.nlm.nih.gov/pubmed/3025598
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