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Identification of Cisplatin-Binding Proteins Using Agarose Conjugates of Platinum Compounds
Cisplatin is widely used as an antineoplastic drug, but its ototoxic and nephrotoxic side-effects, as well as the inherent or acquired resistance of some cancers to cisplatin, remain significant clinical problems. Cisplatin's selectivity in killing rapidly proliferating cancer cells is largely...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Public Library of Science
2013
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Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3670892/ https://ncbi.nlm.nih.gov/pubmed/23755301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066220 |
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