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Systemic Delivery and Biodistribution of Cisplatin in Vivo

Cisplatin is widely used to treat a variety of cancers. However, ototoxicity and nephrotoxicity remain serious side effects of cisplatin-based chemotherapy. In order to inform the study of cisplatin’s off-target effects, a new drug-fluorophore conjugate was synthesized that exhibited utility as a tr...

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Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: Chu, Yu-Hsuan, Sibrian-Vazquez, Martha, Escobedo, Jorge O., Phillips, Amanda R., Dickey, D. Thomas, Wang, Qi, Ralle, Martina, Steyger, Peter S., Strongin, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017860/
https://ncbi.nlm.nih.gov/pubmed/27299507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.6b00240
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