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Calreticulin Binds to Gentamicin and Reduces Drug-Induced Ototoxicity

Aminoglycosides like gentamicin are among the most commonly used antibiotics in clinical practice and are essential for treating life-threatening tuberculosis and Gram-negative bacterial infections. However, aminoglycosides are also nephrotoxic and ototoxic. Although a number of mechanisms have been...

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Hlavní autoři: Karasawa, Takatoshi, Wang, Qi, David, Larry L., Steyger, Peter S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216409/
https://ncbi.nlm.nih.gov/pubmed/21785162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr196
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