Genistein downregulates onco-miR-1260b and inhibits Wnt-signalling in renal cancer cells

BACKGROUND: Wnt-signalling has an important role in renal cancer and it is modulated by genistein in other cancers. Recently, microRNAs (miRNAs) have emerged as new regulators of gene expression. Thus, we focused on miRNAs to examine the regulatory mechanism of genistein on the Wnt-signalling pathwa...

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Hlavní autoři: Hirata, H, Ueno, K, Nakajima, K, Tabatabai, Z L, Hinoda, Y, Ishii, N, Dahiya, R
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
Molecular Diagnostics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670482/
https://ncbi.nlm.nih.gov/pubmed/23591200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.173
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