Genistein downregulates onco-miR-1260b and inhibits Wnt-signalling in renal cancer cells

BACKGROUND: Wnt-signalling has an important role in renal cancer and it is modulated by genistein in other cancers. Recently, microRNAs (miRNAs) have emerged as new regulators of gene expression. Thus, we focused on miRNAs to examine the regulatory mechanism of genistein on the Wnt-signalling pathwa...

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Detalhes bibliográficos
Principais autores: Hirata, H, Ueno, K, Nakajima, K, Tabatabai, Z L, Hinoda, Y, Ishii, N, Dahiya, R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670482/
https://ncbi.nlm.nih.gov/pubmed/23591200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.173
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