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DKK4 activates non-canonical JNK signaling pathway while inhibiting the Wnt-canonical pathway in human renal cell carcinoma

BACHGROUND: The functional significance of Wnt antagonist DICKKOPF-4 (DKK4) has not been investigated in renal cancer. METHODS: We initially found that the expression of DKK4 was significantly higher in renal cancer tissues compared to adjacent normal kidney tissues. To assess the function of DKK4,...

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書誌詳細
出版年:Cancer
主要な著者: Hirata, Hiroshi, Hinoda, Yuji, Majid, Shahana, Chen, Yi, Zaman, Mohd S., Ueno, Koji, Nakajima, Koichi, Tabatabai, Z. Laura, Ishii, Nobuhisa, Dahiya, Rajvir
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871344/
https://ncbi.nlm.nih.gov/pubmed/21472712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.25666
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