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DKK4 activates non-canonical JNK signaling pathway while inhibiting the Wnt-canonical pathway in human renal cell carcinoma
BACHGROUND: The functional significance of Wnt antagonist DICKKOPF-4 (DKK4) has not been investigated in renal cancer. METHODS: We initially found that the expression of DKK4 was significantly higher in renal cancer tissues compared to adjacent normal kidney tissues. To assess the function of DKK4,...
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| Vydáno v: | Cancer |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5871344/ https://ncbi.nlm.nih.gov/pubmed/21472712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.25666 |
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