Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8(+) T cells

The role of CD8(+) T cells in dengue virus infection and subsequent disease manifestations is not fully understood. According to the original antigenic sin theory, skewing of T-cell responses induced by primary infection with one serotype causes less effective response upon secondary infection with...

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Detalhes bibliográficos
Main Authors: Weiskopf, Daniela, Angelo, Michael A., de Azeredo, Elzinandes L., Sidney, John, Greenbaum, Jason A., Fernando, Anira N., Broadwater, Anne, Kolla, Ravi V., De Silva, Aruna D., de Silva, Aravinda M., Mattia, Kimberly A., Doranz, Benjamin J., Grey, Howard M., Shresta, Sujan, Peters, Bjoern, Sette, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670335/
https://ncbi.nlm.nih.gov/pubmed/23580623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305227110
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