Insights into HLA restricted T cell responses in a novel mouse model of dengue virus infection point towards new implications for vaccine design()

The frequency of dengue virus (DENV) infection has increased dramatically in the last few decades, and the lack of a vaccine has led to significant morbidity and mortality worldwide. To date, a convenient murine system to study human T cell responses to DENV has not been available. Mice transgenic f...

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Main Authors: Weiskopf, Daniela, Yauch, Lauren E., Angelo, Michael A., John, Daisy V., Greenbaum, Jason A., Sidney, John, Kolla, Ravi V., De Silva, Aruna D., de Silva, Aravinda M., Grey, Howard, Peters, Bjoern, Shresta, Sujan, Sette, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186824/
https://ncbi.nlm.nih.gov/pubmed/21918184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101970
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