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Role of the ubiquitin ligase E6AP/UBE3A in controlling levels of the synaptic protein Arc
Inactivation of the ubiquitin ligase E6 associated protein (E6AP) encoded by the UBE3A gene has been associated with development of the Angelman syndrome. Recently, it was reported that in mice, loss of E6AP expression results in increased levels of the synaptic protein Arc and a concomitant impaire...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3670309/ https://ncbi.nlm.nih.gov/pubmed/23671107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302792110 |
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