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Alternative ways of modulating JAK-STAT pathway: Looking beyond phosphorylation

Most attempts to develop inhibitors of STAT transcription factors target either activating phosphorylation of tyrosine residue or SH2 domains. However, all six domains of STATs are highly conserved between the species and play important roles in the function of this family of transcription factors....

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Bibliografische gegevens
Hoofdauteurs: Timofeeva, Olga A., Tarasova, Nadya I.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670285/
https://ncbi.nlm.nih.gov/pubmed/24058784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/jkst.22313
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