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Alternative ways of modulating JAK-STAT pathway: Looking beyond phosphorylation
Most attempts to develop inhibitors of STAT transcription factors target either activating phosphorylation of tyrosine residue or SH2 domains. However, all six domains of STATs are highly conserved between the species and play important roles in the function of this family of transcription factors....
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3670285/ https://ncbi.nlm.nih.gov/pubmed/24058784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/jkst.22313 |
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