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Alternative ways of modulating JAK-STAT pathway: Looking beyond phosphorylation
Most attempts to develop inhibitors of STAT transcription factors target either activating phosphorylation of tyrosine residue or SH2 domains. However, all six domains of STATs are highly conserved between the species and play important roles in the function of this family of transcription factors....
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3670285/ https://ncbi.nlm.nih.gov/pubmed/24058784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/jkst.22313 |
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