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The involvement of Galectins in the modulation of the JAK/STAT pathway in myeloproliferative neoplasia

BACKGROUND: In patients with myeloproliferative neoplasia (MPN) the development of fibrosis and increased vessel density correlate with poor prognosis. The JAK2(V617F) mutation constitutively activates JAK2, which phosphorylates signal transducer activator of transcription (STAT), up-regulating vasc...

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Detaylı Bibliyografya
Asıl Yazarlar: Koopmans, Suzanne M, Bot, Freek J, Schouten, Harry C, Janssen, Jannie, van Marion, Arienne MW
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: e-Century Publishing Corporation 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384397/
https://ncbi.nlm.nih.gov/pubmed/22762031
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