Interaction of the oncogenic miR-21 microRNA and the p53 tumor suppressor pathway

MicroRNA-21 (miR-21) is overexpressed virtually in all human cancers and displays oncogenic activity in a transgenic murine model. Similarly, the p53 tumor suppressor gene is the most frequently mutated gene in human cancer, and its loss or mutation leads to tumor formation in mice. To ascertain the...

Full description

Saved in:
Bibliographic Details
Main Authors: Ma, Xiaodong, Choudhury, Saibyasachi N., Hua, Xiang, Dai, Zhongping, Li, Yong
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
Subjects:
Original Manuscript
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670255/
https://ncbi.nlm.nih.gov/pubmed/23385064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt044
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items