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STAT5-mediated self-renewal of normal hematopoietic and leukemic stem cells

The level of transcription factor activity critically regulates cell fate decisions such as hematopoietic stem cell self-renewal and differentiation. The balance between hematopoietic stem cell self-renewal and differentiation needs to be tightly controlled, as a shift toward differentiation might e...

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Autori principali: Schepers, Hein, Wierenga, Albertus T.J., Vellenga, Edo, Schuringa, Jan Jacob
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670129/
https://ncbi.nlm.nih.gov/pubmed/24058747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/jkst.19316
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