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The CDR-H3 repertoire from TdT deficient adult bone marrow is a close, but not exact, homologue of the CDR-H3 repertoire from perinatal liver

When compared to adult bone marrow, the composition of the perinatal liver CDR-H3 repertoire is marked by a paucity of N nucleotides and by enrichment for use of J(H) proximal DQ52; and D(H)-proximal V(H) and J(H) gene segments. To test the extent to which these differences reflect limited perinatal...

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Detalhes bibliográficos
Main Authors: Schelonka, Robert, Ivanov, Ivaylo, Vale, Andre M., Szymanska, Ewa, Zemlin, Michael, Gartland, G. Larry, Schroeder, Harry W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670101/
https://ncbi.nlm.nih.gov/pubmed/20956348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001419
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