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Iron increases the susceptibility of multiple myeloma cells to bortezomib
Multiple myeloma is a malignant still incurable plasma cell disorder. Pharmacological treatment based on proteasome inhibition has improved patient outcome; however, bortezomib-resistance remains a major clinical problem. Inhibition of proteasome functionality affects cellular iron homeostasis and i...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Ferrata Storti Foundation
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3669455/ https://ncbi.nlm.nih.gov/pubmed/23242599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.074872 |
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