The clinical characteristics, therapy and outcome of 85 adults with acute lymphoblastic leukemia and t(4;11)(q21;q23)/MLL-AFF1 prospectively treated in the UKALLXII/ECOG2993 trial

The biology and outcome of adult t(4;11)(q21;q23)/MLL-AFF1 acute lymphoblastic leukemia are poorly understood. We describe the outcome and delineate prognostic factors and optimal post-remission therapy in 85 consecutive patients (median age 38 years) treated uniformly in the prospective trial UKALL...

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Detalhes bibliográficos
Main Authors: Marks, David I., Moorman, Anthony V., Chilton, Lucy, Paietta, Elisabeth, Enshaie, Amir, DeWald, Gordon, Harrison, Christine J., Fielding, Adele K., Foroni, Letizia, Goldstone, Anthony H., Litzow, Mark R., Luger, Selina M., McMillan, Andrew K., Racevskis, Janis, Rowe, Jacob M., Tallman, Martin S., Wiernik, Peter, Lazarus, Hillard M.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2013
Assuntos:
Original Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669452/
https://ncbi.nlm.nih.gov/pubmed/23349309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.081877
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