Prognostic Implications of NOTCH1 and FBXW7 Mutations in Adults With T-Cell Acute Lymphoblastic Leukemia Treated on the MRC UKALLXII/ECOG E2993 Protocol

PURPOSE: Notch pathway activation by mutations in either NOTCH1 and/or FBXW7 is one of the most common molecular events in T-cell acute lymphoblastic leukemia (T-ALL) and, in pediatric disease, predicts for favorable outcome. Their prognostic significance in adult T-ALL is unclear. We sought to eval...

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Detaylı Bibliyografya
Asıl Yazarlar: Mansour, Marc R., Sulis, Maria L., Duke, Veronique, Foroni, Letizia, Jenkinson, Sarah, Koo, Kenneth, Allen, Christopher G., Gale, Rosemary E., Buck, Georgina, Richards, Sue, Paietta, Elisabeth, Rowe, Jacob M., Tallman, Martin S., Goldstone, Anthony H., Ferrando, Adolfo A., Linch, David C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Clinical Oncology 2009
Konular:
Original Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744275/
https://ncbi.nlm.nih.gov/pubmed/19635999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2009.22.0996
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