UKALLXII/ECOG2993: addition of imatinib to a standard treatment regimen enhances long-term outcomes in Philadelphia positive acute lymphoblastic leukemia

The Philadelphia chromosome positive arm of the UKALLXII/ECOG2993 study for adult acute lymphoblastic leukemia (ALL) enrolled 266 patients between 1993 and 2003 (pre-imatinib cohort). In 2003 imatinib was introduced as a single-agent course following induction (N = 86, late imatinib). In 2005 imatin...

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Autores principales: Fielding, Adele K., Rowe, Jacob M., Buck, Georgina, Foroni, Letizia, Gerrard, Gareth, Litzow, Mark R., Lazarus, Hillard, Luger, Selina M., Marks, David I., McMillan, Andrew K., Moorman, Anthony V., Patel, Bella, Paietta, Elisabeth, Tallman, Martin S., Goldstone, Anthony H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2014
Materias:
Clinical Trials and Observations
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916877/
https://ncbi.nlm.nih.gov/pubmed/24277073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-09-529008
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