UKALLXII/ECOG2993: addition of imatinib to a standard treatment regimen enhances long-term outcomes in Philadelphia positive acute lymphoblastic leukemia

The Philadelphia chromosome positive arm of the UKALLXII/ECOG2993 study for adult acute lymphoblastic leukemia (ALL) enrolled 266 patients between 1993 and 2003 (pre-imatinib cohort). In 2003 imatinib was introduced as a single-agent course following induction (N = 86, late imatinib). In 2005 imatin...

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Autori principali: Fielding, Adele K., Rowe, Jacob M., Buck, Georgina, Foroni, Letizia, Gerrard, Gareth, Litzow, Mark R., Lazarus, Hillard, Luger, Selina M., Marks, David I., McMillan, Andrew K., Moorman, Anthony V., Patel, Bella, Paietta, Elisabeth, Tallman, Martin S., Goldstone, Anthony H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2014
Soggetti:
Clinical Trials and Observations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916877/
https://ncbi.nlm.nih.gov/pubmed/24277073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-09-529008
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