The clinical characteristics, therapy and outcome of 85 adults with acute lymphoblastic leukemia and t(4;11)(q21;q23)/MLL-AFF1 prospectively treated in the UKALLXII/ECOG2993 trial

The biology and outcome of adult t(4;11)(q21;q23)/MLL-AFF1 acute lymphoblastic leukemia are poorly understood. We describe the outcome and delineate prognostic factors and optimal post-remission therapy in 85 consecutive patients (median age 38 years) treated uniformly in the prospective trial UKALL...

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Main Authors: Marks, David I., Moorman, Anthony V., Chilton, Lucy, Paietta, Elisabeth, Enshaie, Amir, DeWald, Gordon, Harrison, Christine J., Fielding, Adele K., Foroni, Letizia, Goldstone, Anthony H., Litzow, Mark R., Luger, Selina M., McMillan, Andrew K., Racevskis, Janis, Rowe, Jacob M., Tallman, Martin S., Wiernik, Peter, Lazarus, Hillard M.
格式: Artigo
語言:Inglês
出版: Ferrata Storti Foundation 2013
主題:
Original Articles and Brief Reports
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669452/
https://ncbi.nlm.nih.gov/pubmed/23349309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.081877
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