Frequencies and prognostic impact of RAS mutations in MLL-rearranged acute lymphoblastic leukemia in infants

Lignende værker

• MEK inhibition is a promising therapeutic strategy for MLL-rearranged infant acute lymphoblastic leukemia patients carrying RAS mutations
  af: Kerstjens, Mark, et al.
  Udgivet: (2016)
• Identification of genes transcriptionally responsive to the loss of MLL fusions in MLL-rearranged acute lymphoblastic leukemia.
  af: Marieke H van der Linden, et al.
  Udgivet: (2015-01-01)
• Identification of Genes Transcriptionally Responsive to the Loss of MLL Fusions in MLL-Rearranged Acute Lymphoblastic Leukemia
  af: van der Linden, Marieke H., et al.
  Udgivet: (2015)
• Trametinib inhibits RAS-mutant MLL-rearranged acute lymphoblastic leukemia at specific niche sites and reduces ERK phosphorylation in vivo
  af: Kerstjens, Mark, et al.
  Udgivet: (2018)
• MLL fusion-driven activation of CDK6 potentiates proliferation in MLL-rearranged infant ALL
  af: van der Linden, Marieke H, et al.
  Udgivet: (2014)