The trithorax protein partner menin acts in tandem with EZH2 to suppress C/EBPα and differentiation in MLL-AF9 leukemia

Trithorax and polycomb group proteins antagonistically regulate the transcription of many genes, and cancer can result from the disruption of this regulation. Deregulation of trithorax function occurs through chromosomal translocations involving the trithorax gene MLL, leading to the expression of M...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Thiel, Austin T., Feng, Zijie, Pant, Dhruv K., Chodosh, Lewis A., Hua, Xianxin
Format: Artigo
Jezik:Inglês
Izdano: Ferrata Storti Foundation 2013
Teme:
Original Articles and Brief Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669449/
https://ncbi.nlm.nih.gov/pubmed/23349306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.074195
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki