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The trithorax protein partner menin acts in tandem with EZH2 to suppress C/EBPα and differentiation in MLL-AF9 leukemia

Trithorax and polycomb group proteins antagonistically regulate the transcription of many genes, and cancer can result from the disruption of this regulation. Deregulation of trithorax function occurs through chromosomal translocations involving the trithorax gene MLL, leading to the expression of M...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Thiel, Austin T., Feng, Zijie, Pant, Dhruv K., Chodosh, Lewis A., Hua, Xianxin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Ferrata Storti Foundation 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669449/
https://ncbi.nlm.nih.gov/pubmed/23349306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.074195
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