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Evaluation of ALK Rearrangement in Chinese Non-Small Cell Lung Cancer Using FISH, Immunohistochemistry, and Real-Time Quantitative RT- PCR on Paraffin-Embedded Tissues

Patients with ALK gene rearrangements often manifest dramatic responses to crizotinib, an ALK inhibitor. Accurate identification of patients with ALK-positive non-small cell lung cancer (NSCLC) is essential for the clinical application of ALK-targeted therapy. However, assessing EML4-ALK rearrangeme...

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Detalhes bibliográficos
Main Authors: Zhang, Yun-Gang, Jin, Mu-Lan, Li, Li, Zhao, Hong-Ying, Zeng, Xuan, Jiang, Lei, Wei, Ping, Diao, Xiao-Li, Li, Xue, Cao, Qing, Tian, Xin-Xia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669339/
https://ncbi.nlm.nih.gov/pubmed/23741400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064821
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