Clinical Characteristics and Outcomes of Patients with Primary Lung Adenocarcinoma Harboring ALK Rearrangements Detected by FISH, IHC, and RT-PCR

EML4-ALK is a new driver gene of non-small cell lung cancer and a target of crizotinib. The objectives of this study were to determine the frequency of ALK rearrangements in a large cohort of patients with primary lung adenocarcinoma and to analyze the association of ALK rearrangements with clinicop...

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Détails bibliographiques
Auteurs principaux: Wang, Jinghui, Cai, Yiran, Dong, Yujie, Nong, Jingying, Zhou, Lijuan, Liu, Guimei, Su, Dan, Li, Xi, Wu, Shafei, Chen, Xuejing, Qin, Na, Zeng, Xuan, Zhang, Haiqing, Zhang, Zongde, Zhang, Shucai
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081522/
https://ncbi.nlm.nih.gov/pubmed/24992725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101551
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