Combination of conventional immunohistochemistry and qRT-PCR to detect ALK rearrangement

BACKGROUND: Compared with FISH and qRT-PCR analyses, immunohistochemistry (IHC) is the preferred screening test in most pathology practices for ALK-rearrangement detection. With 100% sensitivity and 98% specificity, the VENTANA ALK (D5F3) IHC assay has been approved in the EU and some Asian countrie...

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Bibliographic Details
Main Authors:	Shan, Ling, Lian, Fang, Guo, Lei, Yang, Xin, Ying, Jianming, Lin, Dongmei
Format:	Artigo
Language:	Inglês
Published:	BioMed Central 2014
Subjects:	Research
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3924409/ https://ncbi.nlm.nih.gov/pubmed/24422905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-1596-9-3
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Combination of conventional immunohistochemistry and qRT-PCR to detect ALK rearrangement

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