Hydrogen Sulfide Prevents Hydrogen Peroxide-Induced Activation of Epithelial Sodium Channel through a PTEN/PI(3,4,5)P(3) Dependent Pathway

Sodium reabsorption through the epithelial sodium channel (ENaC) at the distal segment of the kidney plays an important role in salt-sensitive hypertension. We reported previously that hydrogen peroxide (H(2)O(2)) stimulates ENaC in A6 distal nephron cells via elevation of phosphatidylinositol 3,4,5...

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Detalhes bibliográficos
Main Authors: Zhang, Jianing, Chen, Shuo, Liu, Huibin, Zhang, Bingkun, Zhao, Ying, Ma, Ke, Zhao, Dan, Wang, Qiushi, Ma, Heping, Zhang, Zhiren
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669336/
https://ncbi.nlm.nih.gov/pubmed/23741314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064304
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