The precursor of PI(3,4,5)P(3) alleviates aging by activating daf-18(Pten) and independent of daf-16

Aging is characterized by the loss of homeostasis and the general decline of physiological functions, accompanied by various degenerative diseases and increased rates of mortality. Aging targeting small molecule screens have been performed many times, however, few have focused on endogenous metaboli...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Shi, Dawei, Xia, Xian, Cui, Aoyuan, Xiong, Zhongxiang, Yan, Yizhen, Luo, Jing, Chen, Guoyu, Zeng, Yingying, Cai, Donghong, Hou, Lei, McDermott, Joseph, Li, Yu, Zhang, Hong, Han, Jing-Dong J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479145/
https://ncbi.nlm.nih.gov/pubmed/32901024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18280-4
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