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PTEN and the PI3-Kinase Pathway in Cancer
PI3-kinase and PTEN are major positive and negative regulators, respectively, of the PI3-kinase pathway, which regulates growth, survival, and proliferation. These key signaling components are two of the most frequently mutated proteins in human cancers, resulting in unregulated activation of PI3K s...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2710138/ https://ncbi.nlm.nih.gov/pubmed/18767981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.pathol.4.110807.092311 |
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