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Lamin B1 mediates cell-autonomous neuropathology in a leukodystrophy mouse model
Adult-onset autosomal-dominant leukodystrophy (ADLD) is a progressive and fatal neurological disorder characterized by early autonomic dysfunction, cognitive impairment, pyramidal tract and cerebellar dysfunction, and white matter loss in the central nervous system. ADLD is caused by duplication of...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3668844/ https://ncbi.nlm.nih.gov/pubmed/23676464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66737 |
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