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Engineering improved T cell receptors using an alanine-scan guided T cell display selection system
T cell receptors (TCRs) on T cells recognize peptide-major histocompatibility complex (pMHC) molecules on the surface of antigen presenting cells and this interaction determines the T cell immune response. Due to negative selection, naturally occurring TCRs bind self (tumor) peptides with low affini...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2013
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3668434/ https://ncbi.nlm.nih.gov/pubmed/23500145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2013.02.018 |
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